|
Symbol Name ID |
Mavs
mitochondrial antiviral signaling protein MGI:2444773 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased B cell proliferation |
enlarged spleen |
increased dendritic cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
abnormal B cell physiology |
decreased IgG1 level |
decreased IgG2a level |
increased IgG2a level |
decreased IgG level |
increased IgG level |
increased IgM level |
abnormal macrophage physiology |
abnormal circulating interferon level |
decreased circulating interferon-alpha level |
decreased circulating interferon-beta level |
decreased circulating interferon-gamma level |
increased circulating interferon-gamma level |
decreased circulating interleukin-6 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
abnormal dendritic cell physiology |
abnormal cytokine secretion |
decreased interferon-alpha secretion |
decreased interferon-beta secretion |
decreased interleukin-12 secretion |
decreased interleukin-12b secretion |
decreased interleukin-6 secretion |
decreased tumor necrosis factor secretion |
CNS inflammation |
brain inflammation |
abnormal innate immunity |
abnormal response to infection |
increased susceptibility to Flaviviridae infection induced morbidity/mortality |
increased susceptibility to Flaviviridae infection |
increased susceptibility to Picornaviridae infection |
increased susceptibility to Riboviria infection |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||||
| Mavstm1Aki/Mavstm1Aki | * | ||||||||||||||||||||||||||||||||||||||
| Mavstm1Camb/Mavstm1Camb | |||||||||||||||||||||||||||||||||||||||
| Mavstm1Tsc/Mavstm1Tsc | |||||||||||||||||||||||||||||||||||||||
| Mavstm1Zjc/Mavstm1Zjc | |||||||||||||||||||||||||||||||||||||||
| Mavstm1Zjc/Mavs+ | |||||||||||||||||||||||||||||||||||||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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